(Originally appeared on Medium) Our current system of science publishing works something like this: You design a study, collect the data and write a paper. You submit the manuscript to a peer-reviewed journal. An editor receives, evaluates your paper and decides if it goes out for reviewing by other people in the field, who are … Continue reading When the scientific system fails: predatory journals and an example of authors not doing their job →

(Originally appeared on Medium) I have previously written about the apparent effect of intermittent fasting (IF, or time-restricted feeding, TRF) on IGF-1 and inflammation. Specifically, eating all food during an 8 hour window appeared to lower IGF-1 levels in the absence of significant weight loss. And despite some critics arguing that subjects lost a not-significant … Continue reading Timing matters: early time-restricted feeding (6h) improves insulin sensitivity in the absence of weight loss →

(Originally appeared on Medium) A very interesting new study was published recently on hepatic steatosis (liver fat) and low carbohydrate diets (LCD). Briefly, the researchers tried to understand, using a multi-omics approach, what happened if obese subjects with non-alcoholic fatty liver disease (NAFLD) followed a non-energy restricted diet low in carbohydrates (< 30g per day). … Continue reading Low dietary carbohydrates and liver fat: hold the butter and fat-bombs! →

(Originally appeared on Medium) I have received several comments for my previous post regarding the fact that, based on the body composition data, in the IF group was in a slight calorie deficit and that therefore, the arguments presented in the post were unwarranted. If you haven't read that post, its a discussion on the … Continue reading Why fasting matters: more on IGF-1 →

(Originally appeared on Medium) A very interesting and well designed intermittent fasting (IF) study published last year (hereafter denoted as “this study”) has been widely discussed because of its results on body composition. However, the data in this study shows a lot more if you are interested in health and longevity. There is some debate … Continue reading Why fasting matters: IGF-1 and inflammation →